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Statistical Brief

Number 6

April 2002
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Birth Defects Surveillance System, 1990-1999
West Virginia Residents

The West Virginia Birth Defects Surveillance System (BDSS) was established in 1989 to monitor the occurrence of birth defects among the state's children. The BDSS is housed within the West Virginia Bureau for Public Health and is administered jointly by the Office of Maternal, Child and Family Health and the Office of Epidemiology and Health Promotion.

Using data from the BDSS registry, 5,161 state residents born from 1990 through 1999 were diagnosed with one or more birth defects. Based upon the 214,497 births that occurred to West Virginia residents during that same time period, a rate of 24.1 defects per 1,000 live births results. However, when compared to national figures, the rate is low. In order to produce a more accurate report of the prevalence of birth defects, an effort was made to detect cases of birth defects from other sources. Since the presence of congenital anomalies is noted on the birth certificate, all birth certificate records that indicated a congenital anomaly not already in the BDSS were added to the data set. In addition, any fetal death* record that indicated a congenital anomaly was the underlying cause of death was also added. With these additions, 8,096 West Virginia residents were observed to have one or more birth defects, a rate of 37.7 per 1,000 live births.

Table One
Birth Defects Records by Source
West Virginia Residents, 1990-1999
Year Birth
Defects
Registry
Births
Not in
Registry
Fetal
Deaths
Total
Combined
Records
1990 496 439 16 951
1991 526 266 4 796
1992 449 315 2 766
1993 490 285 0 775
1994 519 283 1 803
1995 566 330 4 900
1996 562 278 5 845
1997 682 270 4 956
1998 471 229 3 703
1999 400 199 2 601
Total 5,161 2,894 41 8,096


* Death of a fetus with a gestational age of at least 20 weeks.

Demographic Factors

A demographic factor that influences the rate of birth defects is maternal age. Women 35 years and older have higher rates of children with birth defects than those of younger ages, 42.2 defects per 1,000 live births, as compared to 37.7 for women of all ages.

Graph of rate of birth defects by age of mother for 1990-1999

The weight of infants at the time of birth is an important factor affecting the rate of birth defects. In infants that weighed less than 1,500 grams (three pounds, five ounces) a rate of 211.6 per 1,000 live births was observed. Babies between 1,500 and 2,499 grams (five pounds, eight ounces) had defects at a rate of 81.2. Of infants who weighed 2,500 grams or more, only 31.8 per 1,000 live births had defects.

Graph showing rate of birth defects by birthweight

There is a marked difference in the rates of birth defects between premature births and infants who are born after a normal gestational period. Children with a gestational age of less than 37 weeks were diagnosed with one or more congenital anomalies at a rate of 92.1 per 1,000 live births. However, those with a gestational age of 37 weeks or more were diagnosed at a rate of 31.9 per 1,000 live births.

Graph of birth defects by gestational age.

There is a measurable difference between the observed rates of birth defects among white mothers and mothers of other races. Children of mothers of other races had a reported rate of birth defects of 48.1 per 1,000 live births, while children of white mothers were observed to have birth defects at a rate of 37.3 per 1,000 live births.

Graph of birth defects by race of mother.

Multiple births is another factor that tends to increase the rate of birth defects. Singleton births produce a rate of 36.8 birth defects per 1,000 live births. In contrast, twins, triplets, and quadruplets collectively have birth defects at a rate of 63.4, nearly twice that of singleton births.

Graph of birth defects by number delivered.

The timeliness of prenatal care affects the rate of birth defects. Those women who received no prenatal care produced children with defects at a rate of 58.3 per 1,000 live births. In contrast, those who began prenatal care in the first trimester of pregnancy gave birth to children with defects at a rate of 36.7 and those who started prenatal care during the second trimester produced children with defects at a rate of 36.2. Those who waited until the third trimester had a birth defect rate of 41.0.

birth defects by onset of prenatal care.

As with timeliness, the quantity of prenatal care affects the rate of birth defects. Those women who visited their obstetricians fewer than 10 times before giving birth produced children with defects at a rate of 41.7 per 1,000 live births. Those who had 10 to 19 prenatal visits gave birth to children with defects at a rate of 34.7. However, those who had 20 or more prenatal visits, most likely those known to have pregnancy complications, produced children with defects at a much higher rate, 53.6 per 1,000 live births.

Graph of rate of birth defects by number of prenatal visits.

The prevalence of birth defects declines as the education level of mothers increases. Mothers with less than 12 years of education gave birth to children with defects at a rate of 39.3 per 1,000 live births. Those with 12 years of education produced children with defects at a rate of 37.2. Mothers who had 13 or more years of education gave birth to children with defects at an even smaller rate, 34.1 per 1,000 live births.

Women who consume alcohol greatly increase the risk of giving birth to children with defects. Children of women who did not consume alcohol had a reported rate of 37.2 birth defects per 1,000 live births. However, women who drank alcoholic beverages during pregnancy gave birth to children with birth defects at an observed rate of 71.6.

Graph of rate of birth defects by mothers' alcohol use.

Children of mothers who smoked during pregnancy have a higher risk of birth defects than those whose mothers did not smoke. Mothers who smoked gave birth to children with birth defects at a rate of 41.6 per 1,000 live births, as compared to a rate of 36.4 among children of mothers who did not smoke during pregnancy.

graph of rate of birth defects by mothers' smoking status


The rate of birth defects by county of residence varies widely (see Table Two). Fayette County had the highest observed rate, 62.0 per 1,000 live births, followed by Raleigh County (56.2) and Berkeley County (54.3). The lowest observed rates were in Mercer County (20.9), Logan County (23.5), and Kanawha County (24.6).

Table Two
Birth Defects by County of Residence
West Virginia Residents, 1990 - 1999
County of
Residence
Births With
Defects
Rate per 1,000
Live Births
County
Rank
County of
Residence
Births With
Defects
Rate per 1,000
Live Births
County
Rank
Barbour 86 48.1 7 Monongalia 414 47.4 10
Berkeley 500 54.3 3 Monroe 38 27.5 48
Boone 100 30.7 39 Morgan 66 45.1 14
Braxton 60 38.7 25 Nicholas 103 34.5 34
Brooke 101 38.3 26 Ohio 286 50.4 5
Cabell 457 38.7 24 Pendleton 30 33.2 36
Calhoun 35 42.7 18 Pleasants 26 29.9 43
Clay 38 28.8 45 Pocahontas 33 32.9 37
Doddridge 33 40.2 21 Preston 154 45.5 12
Fayette 358 62.0 1 Putnam 161 28.1 47
Gilmer 33 44.9 15 Raleigh 495 56.2 2
Grant 59 42.9 17 Randolph 153 46.6 11
Greenbrier 145 36.8 31 Ritchie 39 35.5 33
Hampshire 88 38.1 28 Roane 48 28.4 46
Hancock 95 27.3 50 Summers 53 43.3 16
Hardy 45 31.4 38 Taylor 88 53.3 4
Harrison 328 38.1 27 Tucker 40 49.5 6
Jackson 81 25.9 52 Tyler 31 30.0 41
Jefferson 208 40.9 20 Upshur 108 40.2 22
Kanawha 622 24.6 53 Wayne 202 39.8 23
Lewis 75 37.7 30 Webster 31 27.3 49
Lincoln 77 27.2 51 Wetzel 94 41.1 19
Logan 118 23.5 54 Wirt 19 29.9 44
McDowell 118 30.0 42 Wood 396 36.8 32
Marion 245 37.9 29 Wyoming 147 47.9 8
Marshall 190 47.6 9
Mason 97 33.3 35
Mercer 167 20.9 55 WV Total 8,096 37.7
Mineral 143 45.3 13
Mingo 135 30.3 40
County of
Residence
Births With
Defects
Rate per 1,000
Live Births
County
Rank
County of
Residence
Births With
Defects
Rate per 1,000
Live Births
County
Rank

As with data by county, a wide variance is observed in the reporting of birth defects by hospital of birth (see Table Three). Of hospitals where at least 100 births occurred during the time period of 1990 - 99, the highest observed rates of birth defects were recorded at West Virginia University Hospital, with a rate 92.5 birth defects per 1,000 live births, City Hospital (63.8), and Calhoun General Hospital (63.0). The lowest rates were reported at New River Birthing Center (4.5), Putnam General Hospital (10.0), and Putnam Birthplace (11.8). The difference in rates by hospital may be more a measurement of completeness of reporting than the health of the babies delivered in the various facilities. In addition, birthing centers and smaller hospitals refer high-risk pregnancies to the state's three tertiary care hospitals, i.e., WVU Hospital, CAMC, and Cabell-Huntington Hospital, a possible factor in WVU Hospital's high rate. Other issues such as the quality of prenatal care available at the surveyed facilities may also be factors in rate variation.

 
Table Three
Birth Defects by Hospital1 of Birth by Source of Report
West Virginia Residents, 1990-1999
Hospital of Birth Birth Defects
Registry
Vital
Statistics2
Combined
Birth Defects
Number Rate Number Rate Number Rate Rank
Bluefield Regional Medical Center 89 17.6 28 5.5 117 23.1 30
CAMC - Women & Children's 729 19.9 160 4.4 889 24.3 29
Cabell-Huntington Hospital 586 35.7 93 5.7 679 41.3 8
Calhoun General Hospital 13 54.6 2 8.4 15 63.0 3
Camden-Clark Memorial Hospital 167 22.9 49 6.7 216 29.6 22
City Hospital 410 50.5 108 13.3 518 63.8 2
Davis Memorial Hospital 188 34.9 32 5.9 220 40.9 9
Fairmont General Hospital 136 21.9 23 3.7 159 25.7 26
Grant Memorial Hospital 65 20.7 38 12.1 103 32.8 15
Greenbrier Valley Hospital 89 18.5 72 14.9 161 33.4 13
Jackson General Hospital 11 9.4 12 10.3 23 19.7 33
Jefferson Memorial Hospital 20 10.0 46 23.0 66 33.0 14
Logan General Hospital 70 11.6 51 8.5 121 20.1 32
Monongalia General Hospital 91 20.8 17 3.9 108 24.7 27
New River Birthing Center 0 0.0 1 4.5 1 4.5 37
Ohio Valley Medical Center 63 24.7 31 12.2 94 36.8 10
Pleasant Valley Hospital 25 22.3 14 12.5 39 34.7 11
Preston Memorial Hospital 40 22.7 17 9.6 57 32.3 16
Princeton Community Hospital 27 5.1 62 11.7 89 16.8 34
Putnam Birthplace 2 7.9 1 3.9 3 11.8 35
Putnam General Hospital 1 10.0 0 0.0 1 10.0 36
Raleigh General Hospital 146 8.8 885 53.1 1,031 61.8 4
Reynolds Memorial Hospital 41 21.2 13 6.7 54 27.9 24
Roane General Hospital 13 8.9 23 15.8 36 24.7 28
St. Joseph's Hospital (Wood) 190 39.3 21 4.3 211 43.6 7
St. Joseph's Hospital (Upshur) 56 21.5 26 10.0 82 31.4 18
St. Mary's Hospital 37 9.0 53 12.8 90 21.8 31
Stonewall Jackson Memorial Hospital 67 26.4 14 5.5 81 31.9 17
Summersville Memorial Hospital 31 12.1 36 14.1 67 26.2 25
Thomas Memorial Hospital 162 36.3 35 7.9 197 44.2 6
United Hospital Center - Downtown 171 18.0 127 13.4 298 31.4 19
Weirton Medical Center 52 20.8 24 9.6 76 30.4 21
Welch Emergency Hospital 26 13.4 31 16.0 57 29.4 23
West Virginia University Hospital 728 69.6 240 22.9 968 92.5 1
Wetzel County Hospital 32 19.6 18 11.0 50 30.6 20
Wheeling Hospital 339 47.6 18 2.5 357 50.1 5
Williamson Memorial Hospital 23 16.1 26 18.2 49 34.3 12
West Virginia Total 5,161 24.1 2,935 13.7 8,096 37.7

Hospital of Birth
Number Rate Number Rate Number Rate Rank
Birth Defects
Registry
Vital
Statistics2
Combined
Birth Defects
1. Only hospitals with at least 100 births from 1990 through 1999 are included.
2. Birth records indicating a congenital anomaly not in the birth defects registry.

This brief is intended only to provide statistical data on the numbers and rates of reported birth defect incidences from 1990-99 and does not include services available for children who have been affected. For more information on services available, please contact the Office of Maternal, Child and Family Health at 1-800-642-8522.

If you have questions concerning the content of this page, please contact the Health Statistics Center at (304) 558-9100 or dhhrvitalreg@wv.gov.

This page was last updated 04/23/02.

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